WHO WE SELL TO
Our high-quality prints and custom canvases available to the trade includes: art dealers, not-for profits, retailers, and design professionals. We require you to register and provide tax exempt paperwork as necessary. The trade may also purchase retail prints offered to the public. Please contact us for information on retail minimums and wholesale purchases.
SHIPPING & RETURNS
Orders are typically processed and shipped within 1 week. For larger custom orders an estimated timeframe will be provided. Upon shipment, tracking information will be sent via email. While we do not accept Wholesale returns, damaged items will be exchanged for new products. For instructions on how to issue a return request, please contact customer service.
Basophil: Basophils are the largest granulocyte and make up about 0.5-1% of circulating white blood cells in the body. They are part of the inflammatory response and coordinated immune response. Basophils are created and mature within the bone marrow. They have large cytoplasmic granules and a two-lobed nucleus. Cell surface proteins bind immunoglobulin, IgE, and help to mediate the secondary immune response. Basophils store histamine, a vasodilator and heparin, an anticoagulant. They can be recruited into tissues from circulating blood when needed to respond to allergic reactions.
Eosinophil: Eosinophils are a type of white blood cell that controls immune responses to allergies and asthma. They develop in the bone marrow during hematopoiesis and migrate into the blood where they will terminally differentiate and reside in tissue. They make up about 1-3% of white blood cells with bilobed nuclei.
Erythrocyte: Erythrocytes, also known as red blood cells (RBCs) are the most common type of blood cell and are responsible for delivering oxygen from the lungs to tissues through the circulatory system. RBC cytoplasm contains hemoglobin, a molecule containing iron to bind oxygen and give cells and blood their red color. They have an oval biconcave disk shape and lack a nucleus. Approximately 2.4 million new RBCs are created each second in the bone marrow. Cells circulate for 100-200 days before they are broken down and disposed of. They make up almost half of the blood’s volume and 84% of total cells in the human body.
Lymphocyte: Lymphocytes are a subtype of white blood cells which include natural killer cells, T cells, and B cells. They are the main cell in lymph, the fluid that flows through the lymphatic system. Various lymphocytes can be identified by their large nucleus. All lymphocytes are created in the bone marrow during hematopoiesis and come from a common progenitor before they differentiate into their distinct cell types in various regions in the body. Lymphocytes are known for their role in adaptive immunity as well as their differentiation after antigen exposure.
Macrophage: Macrophages are a type of white blood cell that digests pathogens and cellular debris through phagocytosis. They are found in almost all tissues and play a crucial role in innate immunity as well as in the initiation of adaptive immunity mechanisms through the recruiting of other cell types. Macrophages can both increase inflammation as well as decrease immune reactions by using differing types of macrophages. They are produced by circulating monocytes and differentiate into various forms within tissues.
Mast Cell: Mast cells are a type of granulocyte that plays a role in the immune system, wound healing and angiogenesis. They are found in most tissues surrounding blood vessels and nerves, specifically the skin, lungs, digestive tract, mouth and nose, as well as in the neuroimmune system in the brain. Mast cells are key players in the inflammatory process. When activated, they act as mediators to induce inflammation.
Monocyte: Monocytes are a type of white blood cell that differentiates into macrophages and dendritic cells. They have a large nucleus and cytoplasm with their main functions being phagocytosis, antigen presentation and cytokine production. They are involved in the innate immune system as well as play an influential role in the adaptive immune system. They are created in the bone marrow from monoblasts and move to circulating in the bloodstream for 1-3 days followed by tissues where they will continue to differentiate. Monocytes are responsible for protection against foreign substances and in the formation of various organs.
Natural Killer Cell: Natural killer (NK) cells are cytotoxic lymphocytes involved in the innate immune system by providing a rapid response to virus-infected cells and tumor formation. They are able to recognize stressed cells at day three days post-infection. NK cells are unique in that they do not require activation markers. NK cells differentiate and mature from a lymphoid progenitor in the bone marrow, lymph nodes, spleen, tonsils and thymus and then move into the bloodstream to circulate.
Neutrophil: Neutrophils are a type of granulocyte and make up 50-70% of white blood cells in the body. They play a role in the innate immune system. Neutrophils are formed in the bone marrow and differentiated into various cell types. They have phagocytic properties and are part of the first inflammatory response at the site of injury.
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